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Dynamics of Hole Trapping by G, GG, and GGG in DNA

✍ Scribed by William B. Davis; Izabela Naydenova; Reinhard Haselsberger; Alexander Ogrodnik; Bernd Giese; Maria E. Michel-Beyerle


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
128 KB
Volume
112
Category
Article
ISSN
0044-8249

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Oxidative damage to DNA by ionizing radiation, carcinogenic agents, and photosensitizers occurs predominately at guanine (G) bases, [1, 2] a result which can be rationalized by the hierarchy of in vitro oxidation potentials of the isolated nucleobases (G < A ( C,T). [3] Strand cleavage reactions, in

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