Dynamics and Energetics of Hole Trapping in DNA by 7-Deazaguanine
β Scribed by Frederick D. Lewis; Jianqin Liu; Xiaoyang Liu; Xiaobing Zuo; Ryan T. Hayes; Michael R. Wasielewski
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 75 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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Oxidative damage to DNA by ionizing radiation, carcinogenic agents, and photosensitizers occurs predominately at guanine (G) bases, [1, 2] a result which can be rationalized by the hierarchy of in vitro oxidation potentials of the isolated nucleobases (G < A ( C,T). [3] Strand cleavage reactions, in
## Abstract RNA and DNA molecules experience motions on a wide range of time scales, ranging from rapid localized motions to much slower collective motions of entire helical domains. The many functions of RNA in biology very often require this molecule to change its conformation in response to biol