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Dynamics of DNA polymerase I (Klenow fragment) under external force

โœ Scribed by Ping Xie


Book ID
120923101
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
613 KB
Volume
19
Category
Article
ISSN
1610-2940

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A domain of the klenow fragment of Esche
โœ P. S. Freemont; Dr. D. L. Ollis; T. A. Steitz; C. M. Joyce ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 868 KB

The Klenow fragment of DNA polymerase I from Escherichia coli has two enzymatic activities: DNA polymerase and 3'-5' exonuclease. The crystal structure showed that the fragment is folded into two distinct domains. The smaller domain has a binding site for deoxynucleoside monophosphate and a divalent