Duodenal delivery of levodopa for on-off
β
Dr Roger Kurlan; Allen J. Rubin; Charlyne Miller; Leonor Rivera-Calimlim; Allan
π
Article
π
1986
π
John Wiley and Sons
π
English
β 418 KB
π 2 views
The pathogenesis of on-off motor fluctuations in parkinsonism remains incompletely understood, but slowed or erratic gastric emptying of orally administered levodopa may be involved. In 3 patients with resistant on-off fluctuations, direct duodenal continuous infusion of levodopa via a nasoduodenal