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Long-term duodenal infusion of levodopa for motor fluctuations in parkinsonism

โœ Scribed by Dr. J. I. Sage; S. Trooskin; P. K. Sonsalla; R. Heikkila; R. C. Duvoisin


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
365 KB
Volume
24
Category
Article
ISSN
0364-5134

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Duodenal delivery of levodopa for on-off
โœ Dr Roger Kurlan; Allen J. Rubin; Charlyne Miller; Leonor Rivera-Calimlim; Allan ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 418 KB ๐Ÿ‘ 1 views

The pathogenesis of on-off motor fluctuations in parkinsonism remains incompletely understood, but slowed or erratic gastric emptying of orally administered levodopa may be involved. In 3 patients with resistant on-off fluctuations, direct duodenal continuous infusion of levodopa via a nasoduodenal