Cultured astrocytes express bradykinin (BK) receptors, which are coupled to phospholipase C (PLC) through G-protein to mediate phosphoinositide (PI) hydrolysis. The regulation of this BK receptor-G protein-PLC pathway by CAMP and endothelin-1 (ET-1) was explored by short-term (20 min) and long-term
โฆ LIBER โฆ
Dual elevation of cyclic AMP and inositol phosphates in response to mechanical deformation of murine osteoblasts
โ Scribed by Jonathan R. Sandy; Sajeda Meghji; Richard W. Farndale; Murray C. Meikle
- Book ID
- 119120986
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 709 KB
- Volume
- 1010
- Category
- Article
- ISSN
- 0167-4889
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## Abstract Isolated newborn rat calvarial bone cells grown in monolayer on polyurethane membranes in specially constructed culture chambers and subjected to a cyclical biaxial mechanical strain of 0.17% at a frequency of 1 Hz for 30 min demonstrated a 16% increase in DNA synthesis during the subse