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Dissociation of renal cyclic AMP and phosphate responses to parathyroid hormone in uremia

✍ Scribed by J. E. Russell; M. Kleerekoper; E. Slatopolsky; J. Lewis; S. W. Lee; L. V. Avioli


Publisher
Springer
Year
1979
Tongue
English
Weight
653 KB
Volume
29
Category
Article
ISSN
1432-0827

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Rats fed a diet deficient in vitamin D were found t o exhibit a refractory cyclic AMP response of kidney slices to parathyroid hormone and a marked decrease in membrane parathyroid hormone-dependent adenylate cyclase activity. Both the characteristic calcium deficiency (hypocalcemia) and secondary e