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Dual Aromatase−Steroid Sulfatase Inhibitors

✍ Scribed by Woo, L. W. Lawrence; Bubert, Christian; Sutcliffe, Oliver B.; Smith, Andrew; Chander, Surinder K.; Mahon, Mary F.; Purohit, Atul; Reed, Michael J.; Potter, Barry V. L.


Book ID
111962883
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
630 KB
Volume
50
Category
Article
ISSN
0022-2623

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Aromatase and Dual Aromatase-Steroid Sul
✍ Dr. Paul M. Wood; Dr. L. W. Lawrence Woo; Dr. Mark P. Thomas; Dr. Mary F. Mahon; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 922 KB

Concurrent inhibition of aromatase and steroid sulfatase (STS) may provide a more effective treatment for hormone-dependent breast cancer than monotherapy against individual enzymes, and several dual aromatase–sulfatase inhibitors (DASIs) have been reported. Three aromatase inhibitors with sub-nanom