The most important objective of the Hungarian CaseΒ±Control Surveillance of Congenital Abnormalities is the postmarketing surveillance of the teratogenic eects of drugs. This dataset includes 22,865 pregnant women who had ospring with congenital abnormalities and 38,151 pregnant women who had healthy
Drug use in pregnancy: an overview of epidemiological (drug utilization) studies
β Scribed by M. Bonati; R. Bortolus; F. Marchetti; M. Romero; G. Tognoni
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 399 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0031-6970
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β¦ Synopsis
The need for further information on drug utilization patterns during pregnancy in different countries was assessed by reviewing literature obtained by hand and computer searches for the years 1960-1988. The 13 identified studies showed that pregnant women used an average of 4.7 drugs. The most commonly ingested medications were vitamins and iron preparations (almost all women), analgesics, antiemetics and antacids. However, the important variables taken into account differently in each study, such as date of surveillance, country, size of population, personal habits, and physiopathological and demographic characteristics, may it impossible to construct a comprehensive, detailed, up-to-date picture of drug utilization during pregnancy. The evaluation confirmed the need for systematic permanent surveillance of drug utilization in pregnancy, so as to avoid the use of data based on widely differing contexts, times and methods, in a field where knowledge is often derived from scanty information.
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We have compared the reliability of the information about drug therapy and pregnancy retrieved by interviewing patients with that distilled from pharmacy records. In the initial phase of each interview we used the internationally accepted open-ended technique, and extended this with an indication-or