Internal reference compounds labeled with stable isotopes have been used to quantify drugs and drug metabolites in urine, plasma and breast milk. [2,4,5J%&]Diphenylhydantoin, [2,4,5J3C3]phenobarbital and [I-CZH3]valium have been used to quantify diphenylhydantoin, phenobarbital and Valium, respectiv
Use of stable isotopes in drug disposition studies in man
β Scribed by Leif Bertilsson
- Publisher
- Elsevier Science
- Year
- 1988
- Weight
- 84 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0883-2889
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The use of stable isotopes to estimate evapotranspiration "ET# ~uxes from vegetated areas is increasing[ By complementing conventional net ~ux measurements "gradient or eddy correlation techniques#\ isotope analyses can allow partitioning ET between its gross components\ soil evaporation and leaf tr
CGS 15873 is a relatively specific dopamine agonist with preferential activity at the presynaptic autoreceptor and therefore may represent a novel agent for the treatment of schizophrenia and/or Parkinson's disease. Several metabolites have been identified in the rat and monkey using an isotopically