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Drug Salts and Solubilization: Modeling the Influence of Cyclodextrins on Oral Absorption

✍ Scribed by Ece Dilber Gamsiz; Avinash G. Thombre; Imran Ahmed; Rebecca Lyn Carrier


Publisher
Springer
Year
2010
Tongue
English
Weight
729 KB
Volume
39
Category
Article
ISSN
0090-6964

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Modeling the influence of cyclodextrins
✍ Ece Dilber Gamsiz; Lee Miller; Avinash G. Thombre; Imran Ahmed; Rebecca Lyn Carr πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 744 KB

## Abstract The ability to quantitatively predict the influence of a solubilization technology on oral absorption would be highly beneficial in rational selection of drug delivery technology and formulation design. Cyclodextrins (CDs) are cyclic oligosaccharides which form inclusion complexes with

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## Abstract A model was developed for predicting the influence of cyclodextrins (CDs) delivered as a physical mixture with drug on oral absorption. CDs are cyclic oligosaccharides which form inclusion complexes with many drugs and are often used as solubilizing agents. The purpose of this work is t

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