Drug Identification through in vivo Screening of Chemical Libraries

Drug Identification through in vivo Scre

✍ Darren M. Brown; Maurizio Pellecchia; Erkki Ruoslahti 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 120 KB

Specific cell-surface molecules can direct leukocytes and certain tumor cells to particular organs. [1±3] Recent work by our group has shown that peptides, selected by using the in vivo phage-screening approach, are also capable of mediating selective in vivo localization of phage to individual orga

The Simultaneous Determination of Mixtur

The Simultaneous Determination of Mixtures of Drug Candidates by Liquid Chromatography/Atmospheric Pressure Chemical Ionization Mass Spectrometry as an In Vivo Drug Screening Procedure

✍ Timothy V. Olah; Debra A. McLoughlin; John D. Gilbert 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 128 KB 👁 2 views

Liquid chromatography, combined with tandem mass spectrometry (LC/MS/MS) has been rapidly embraced by the pharmaceutical industry as the definitive method for the determination of drug levels in biological fluids obtained from pharmacokinetic and toxicological studies. This technique has proved to b

Pharmacophore Identification, in Silico

Pharmacophore Identification, in Silico Screening, and Virtual Library Design for Inhibitors of the Human Factor Xa.

✍ Eva M. Krovat; Karin H. Fruehwirth; Thierry Langer 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 8 KB 👁 2 views

ChemInform Abstract: Identification of a

ChemInform Abstract: Identification of a Potent and Selective Oxytocin Antagonist, from Screening a Fully Encoded Differential Release Combinatorial Chemical Library.

✍ Brian Evans; Adrian Pipe; Liz Clark; Martyn Banks 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: Synthesis of a Libr

ChemInform Abstract: Synthesis of a Library of β-GlcNAc Glycosides to Screen for Efficient in vivo Glycosyltransferase Acceptors.

✍ Yili Ding; Yoshiaki Miura; James R. Etchison; Hudson H. Freeze; Ole Hindsgaul 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB

ChemInform Abstract: Ti-Catalyzed Regio-

ChemInform Abstract: Ti-Catalyzed Regio- and Enantioselective Synthesis of Unsaturated α-Amino Nitriles, Amides and Acids. Catalyst Identification Through Screening of Parallel Libraries.

✍ James R. Porter; Wolfgang G. Wirschun; Kevin W. Kuntz; Marc L. Snapper; Hoveyda 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v