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Drug Discovery and Development in the Age of Molecular Medicine

โœ Scribed by Vallance, P; Levick, M


Book ID
110020189
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
347 KB
Volume
82
Category
Article
ISSN
0009-9236

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Drug discovery and development, Vol. 1:
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Drug Discovery and Development, edited by M.S. Chorghade, is a two volume set, the first of which is now available. Volume 1, Drug Discovery, is composed of 16 chapters by authors who are active in the field of medicinal chemistry and are able to bring historical perspective to this important field

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## Abstract Metabolism by the host organism is one of the most important determinants of the pharmacokinetic profile of a drug. High metabolic lability usually leads to poor bioavailability and high clearance. Formation of active or toxic metabolites will have an impact on the pharmacological and t