Drug discovery and development, Vol. 1: Drug discovery

✍ Scribed by Robert H. Glew

• Publisher: The American Society for Biochemistry and Molecular Biology
• Year: 2007
• Tongue: English
• Weight: 25 KB
• Volume: 35
• Category: Article
• ISSN: 1470-8175
• DOI: 10.1002/bmb.38

✦ Synopsis

Drug Discovery and Development, edited by M.S. Chorghade, is a two volume set, the first of which is now available. Volume 1, Drug Discovery, is composed of 16 chapters by authors who are active in the field of medicinal chemistry and are able to bring historical perspective to this important field of chemistry. Chapter 2 ''Medicinal Chemistry in the New Millenium: A Glance into the Future'' by Paul Erhardt is a long chapter that places the other chapters into context and gives the reader numerous examples of drug development that help to make the important teaching points of this book clear and meaningful. This is not a textbook, however, and is not designed to teach the synthetic organic chemistry and physical organic chemistry that underpin medicinal chemistry. Nevertheless, there are numerous sections on synthetic chemistry as applied to drug development, especially in some of the later chapters that are devoted to development of specific drugs.

Undergraduate students and graduate students can learn much from this well-written collection of articles, especially if the book is used as a reference source in a seminar course designed to introduce the field of medicinal chemistry. This would be especially the case in Departments of Chemistry that traditionally do not offer courses in medicinal chemistry. The ever-changing field of medicinal chemistry is impacted by many other disciplined and emerging technologies, such that graduating undergraduates from traditional chemistry programs may not appreciate the challenges of modern medicinal chemistry and where this field will likely change in the future. This volume can help students to bridge this gap in their understanding of chemistry.