Drug absorption VI: Water flux and drug
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S. Kojima; R. B. Smith; W. G. Crouthamel; J. T. Doluisio
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Article
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1972
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John Wiley and Sons
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English
โ 423 KB
XIII) similar to IX of the classical mechanism except for saturation of the 5,6-bond, but it may be favored since 6-position attack by hydroxide ions on uracils and pyrimidine nucleosides is well documented (4, 6, 8). The resultant active intermediate (IX or XII) may deaminate (XI1 -. XIII -+ XIV +