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Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

✍ Scribed by Xu, Dawei; Wang, Qian; Gruber, Astrid; Björkholm, Magnus; Chen, Zhiguo; Zaid, Ahmed; Selivanova, Galina; Peterson, Curt; Wiman, Klas G; Pisa, Pavel

Book ID: 110064202
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 334 KB
Volume: 19
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1203890

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## Abstract ## BACKGROUND The objectives of this study were to evaluate the diagnostic and prognostic relevance of human telomerase reverse transcriptase (hTERT) detected in situ in patients with nonsmall cell lung carcinoma (NSCLC) and to investigate the possible correlations between hTERT mRNA i