Loss of heterozygosity and human telomer
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Linda Capkova; Marketa Kalinova; Lenka Krskova; Daniela Kodetova; Frantisek Petr
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Article
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2007
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John Wiley and Sons
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English
โ 249 KB
## Abstract ## BACKGROUND Lung carcinogenesis is a multistep process of accumulation of genetic changes, including loss of heterozygosity (LOH), and precedes phenotypic transformation of the bronchial mucosa. The activity of telomerase, correlating with the hTERT mRNA expression, is detectable in