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Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells

✍ Scribed by Gum-Yong Kang; Eung-Ryoung Lee; Jung-Hyun Kim; Jin Woo Jung; Jun Lim; Sang Kyung Kim; Ssang-Goo Cho; Kwang Pyo Kim

Book ID
113588203
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
370 KB
Volume
611
Category
Article
ISSN
0014-2999

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Estrogens are mitogenic for estrogen receptor (ER)-positive breast cancer cells. Current treatment of ER-positive breast tumors is directed towards interruption of estrogen activity. We report that treatment of ER-positive breast cancer cells with kaempferol resulted in a time- and dose-dependent de