Down syndrome screening in an asian population using alpha-fetoprotein and free β-hcg: a report of the taiwan down syndrome screening group
✍ Scribed by Jenn J. Hsu; T'sang T. Hsieh; Fon J. Hsieh
- Book ID
- 116039341
- Publisher
- Lippincott Williams and Wilkins
- Year
- 1996
- Tongue
- English
- Weight
- 578 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0029-7844
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This study is a novel approach in establishing the maternal age-specific risk for Down syndrome screening in an Asian population. The relative frequency by one-year maternal age interval in women who had live births in the Taiwan area between 1975 and 1995 was used as the age-specific distribution o
High free beta human chorionic gonadotropin ( -hCG) and low alpha-fetoprotein (AFP) levels were found in 47 Asian Down's syndrome pregnancies (median values 2•79 and 0•77 MOM, respectively). At a 5 per cent false-positive rate, free -hCG alone would identify 46•8 per cent of Down's syndrome pregnanc