The use of free β-hCG in antenatal screening for Down's syndrome
✍ Scribed by K. Spencer; J. N. Macri
- Book ID
- 111156281
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 167 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1470-0328
No coin nor oath required. For personal study only.
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Published studies have reached varying conclusions as to the benefit of replacing human chorionic gonadotropin (hCG) measurements with the free -subunit of hCG (the free -subunit) for Down syndrome screening. One study reports 14 per cent higher detection for the free -subunit, while another finds a
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Biochemical screening for Down syndrome (DS) is well established in the second trimester of pregnancy, but there is little information available on its value in the first trimester. This study describes our preliminary results with biochemical screening for DS in the first trimester of pregnancy in