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Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α-kinoid

✍ Scribed by Lauwerys, Bernard R.; Hachulla, Eric; Spertini, François; Lazaro, Estibaliz; Jorgensen, Christian; Mariette, Xavier; Haelterman, Edwige; Grouard-Vogel, Géraldine; Fanget, Bernard; Dhellin, Olivier; Vandepapelière, Pierre; Houssiau, Frédéric A.


Book ID
118752782
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
825 KB
Volume
65
Category
Article
ISSN
0004-3591

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## Abstract ## Objective Gene‐expression studies have demonstrated increased expression of interferon (IFN)–inducible genes (IFIGs) in peripheral blood mononuclear cells (PBMCs) of many patients with systemic lupus erythematosus (SLE), with a predominant effect of type I IFN. This study examined t