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Dose–response of alkylation-induced colorectal carcinogenesis in MGMT-proficient and -deficient mice

✍ Scribed by Fahrer, Jörg; Frisch, Janina; Nagel, Georg; Reißig, Sonja; Waisman, Ari; Samson, Leona D.; Kaina, Bernd


Book ID
122993605
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
71 KB
Volume
221
Category
Article
ISSN
0378-4274

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## Abstract **Scope:** Curcumin is a polyphenol with a variety of pharmacologic effects. We evaluate the effect of dietary curcumin on the severity of repeated colitis‐associated colorectal cancer. **Methods and results:** Six‐week‐old C57BL/6 mice were randomized into two dietary groups: standard