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Dose-response of retinoic acid induced stress protein synthesis and teratogenesis in mice

✍ Scribed by Deborah K. Hansen; James B. LaBorde; Kelly S. Wall; William G. Hinson; James L. Pipkin; Joe Shaddock; Lascelles Lyn-Cook; John F. Young

Book ID: 114273719
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 812 KB
Volume: 15
Category: Article
ISSN: 0890-6238
DOI: 10.1016/s0890-6238(00)00118-0

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## Background: Prenatal rat embryo exposure to retinoids induces severe malformations in various organs; the most active and teratogenic metabolite is all-trans-retinoic acid (atra). the mechanisms of this embryopathy are only partly known. in the present study, the influence of glycine on the tera