𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins

✍ Scribed by Bugni, J M; Meira, L B; Samson, L D

Book ID
109970758
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
352 KB
Volume
28
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Helicobacter hepaticus promotes azoxymet
Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/c-IL10-deficient mice
✍ Claude M. Nagamine; Arlin B. Rogers; James G. Fox; David B. Schauer 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 294 KB

## Abstract The BALB/c‐IL10 null mouse strain develops colitis and colitis‐associated adenocarcinomas, and is a model for idiopathic inflammatory bowel disease. We tested the hypotheses that (__i__) azoxymethane (AOM), a carcinogen that targets the colon, synergizes with the colonic inflammation in

Genetic reduction of circulating insulin
Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice
✍ Susan E. Olivo-Marston; Stephen D. Hursting; Jackie Lavigne; Susan N. Perkins; R 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB

## Abstract High levels of insulin‐like growth factor‐1 (IGF‐1) have been associated with a significant increase in colon cancer risk. Additionally, IGF‐1 inhibits apoptosis and stimulates proliferation of colonic epithelial cells in vitro. Unfortunately, IGF‐1 knockout mice have severe development