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Dose-rate effects of ethyl methanesulfonate on induction of 6-thioguanine-resistant mutations in cultured Chinese hamster cells

✍ Scribed by Y. Kuroda; K. Sugiura


Book ID
113249361
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
137 KB
Volume
53
Category
Article
ISSN
0165-1161

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The temporal sequence of mutation to 6-thioguanine resistance was studied in Chinese hamster ovary cells synchronised in S phase. The number of resistant mutants induced following exposure to pulses of bromodeoxyuridine and subsequent selection was significantly greater if BUdR pulses were administe