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Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis

✍ Scribed by G. V. Campion; M. E. Lebsack; J. Lookabaugh; G. Gordon


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
991 KB
Volume
39
Category
Article
ISSN
0004-3591

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## Objective: Patients with rheumatoid arthritis (ra) have defective hypothalamic responses to inflammation, possibly because of excessive production of cytokine inhibitor, which could blunt the effects of cytokines on the hypothalamus, or because of an imbalance between interleukin-1 beta (il-1 be