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A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: Radiologic progression and correlation of genant and larsen scores

✍ Scribed by Yebin Jiang; Harry K. Genant; Iain Watt; Mark Cobby; Barry Bresnihan; Roger Aitchison; Dorothy McCabe


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
78 KB
Volume
43
Category
Article
ISSN
0004-3591

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MLN3897 plus methotrexate in patients wi
✍ Clarissa E. Vergunst; Danielle M. Gerlag; Lisa von Moltke; Michael Karol; Tim Wy πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 169 KB πŸ‘ 2 views

## Abstract ## Objective To assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of the CC chemokine receptor CCR1 antagonist MLN3897 in patients with rheumatoid arthritis (RA) receiving methotrexate (MTX). ## Methods In this phase IIa, proof‐of‐concept study, patients meeting the