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Dopamine-Endocrine and Oncogenic Functions

✍ Scribed by Nira Ben-Jonathan (Author)


Publisher
CRC Press
Year
2020
Leaves
438
Edition
1
Category
Library

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✦ Synopsis


Dopamine is a small molecule traditionally regarded as a brain-derived neuronal modulator implicated in many neurological and psychiatric disorders. Outside the brain, dopamine fulfills all the criteria of a circulating hormone which affects normal and abnormal functions of multiple organs and regulatory systems and is also involved in many aspects of cancer formation and progression. This book provides a much needed systematic account of dopamine as an endocrine and autocrine/paracrine hormone and fills a major gap in the overall understanding of the production, distribution and actions of this very important molecule.

Key Features:

  • Explores the many different faces of dopamine as autocrine, paracrine and endocrine molecule
  • Documents the adverse effects of antipsychotics on dopamine functions
  • Reviews the many ways dopamine affects the cardiovascular, renal and reproductive systems
  • Provides updates on receptor oligomerization and signaling
  • Examines the role of dopamine in tumorigenesis

Related Titles

Jones, S. ed. Dopamine - Glutamate Interactions in the Basal Ganglia (ISBN 978-0-3673-8197-4)

Luo, L. Principles of Neurobiology (ISBN 978-0-8153-4494-0)

Sidhu, A. et al., eds. Dopamine Receptors and Transporters (ISBN 978-0-8247-0854-2)

✦ Table of Contents


Chapter 1: Homeostasis of dopamine.

Chapter 2: Dopamine receptors and their signaling.

Chapter 3: Anatomical and endocrine aspects of brain dopamine.

Chapter 4: Attributes of peripheral dopamine.

Chapter 5: Renal and cardiovascular functions of dopamine.

Chapter 6: Digestive and metabolic actions of dopamine.

Chapter 7: Dopamine and hematopoiesis.

Chapter 8: Regulation of reproduction by dopamine.

Chapter 9: Cutaneous actions of dopamine.

Chapter 10: Dopamine and tumorigenesis in reproductive tissues.

Chapter 11: Dopamine, hematologic and GI-related cancers.

Chapter 12: Actions of dopamine on other cancers. Summary and Perspectives


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