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Dopamine D4 receptor subtypes and response to clozapine

โœ Scribed by Shaikh, S.; Collier, D.; Kerwin, R.W.; Pilowsky, L.S.; Gill, M.; Xu, W-M.; Thornton, A.

Book ID
122910474
Publisher
The Lancet
Year
1993
Tongue
English
Weight
164 KB
Volume
341
Category
Article
ISSN
0140-6736

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## Abstract We have examined the hypothesis that a variable number of tandem repeats in the third cytoplasmic loop of the dopamine D4 receptor influences clinical response to clozapine using a sample of 189 schizophrenic patients. Alleles of the 48โ€bp repeat, which range from two to ten copies in t