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Dopamine D3 receptor gene polymorphism and response to clozapine in schizophrenic Pakistani patients

✍ Scribed by Joachim Scharfetter; Haroon R Chaudhry; Kurt Hornik; Karoline Fuchs; Werner Sieghart; Siegfried Kasper; Harald N Aschauer

Book ID
118601143
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
51 KB
Volume
10
Category
Article
ISSN
0924-977X

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Analysis of clozapine response and polym
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## Abstract We have examined the hypothesis that a variable number of tandem repeats in the third cytoplasmic loop of the dopamine D4 receptor influences clinical response to clozapine using a sample of 189 schizophrenic patients. Alleles of the 48‐bp repeat, which range from two to ten copies in t