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Dopamine D2 and D3 Receptor Occupancy in Normal Humans Treated with the Antipsychotic Drug Aripiprazole (OPC 14597): A Study Using Positron Emission Tomography and [11C]Raclopride

✍ Scribed by Fuji Yokoi; M.D Ph.D; Gerhard Gründer; Kathleen Biziere; Massoud Stephane; Ahmet S Dogan; Robert F Dannals; Hayden Ravert; Ajit Suri; Steven Bramer; Dean F Wong


Book ID
114281006
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
273 KB
Volume
27
Category
Article
ISSN
1470-634X

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## Abstract We used [^11^C]raclopride (RACLO) and positron emission tomography (PET) to study longitudinally striatal dopamine D~2~ receptor binding in nine patients with Parkinson's disease (PD) at an early drug‐naive stage and 3–5 years later, when motor fluctuations had appeared in seven of them