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Dopamine D1 Agonist SKF 38393 Increases the State of Phosphorylation of ARPP-21 in Substantia Nigra

✍ Scribed by Kang Tsou; Jean-Antoine Girault; Paul Greengard


Book ID
111177777
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
603 KB
Volume
60
Category
Article
ISSN
0022-3042

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The effects of the D-1 agonist SKF 38393 on tonic activity of rat substantia nigra pars compacta dopamine neurons were studied using extracellular, single-unit recording techniques. Unlike nonselective D-1/D-2 dopamine agonists or the D-2 agonist quinpirole, SKF 38393 did not inhibit dopamine neuron