𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dopamine D-2 receptors imaged by PET in Cebus apella using [18F]benzamide neuroleptic

✍ Scribed by Jogeshwar Mukherjee; Karen E. Luh; Nicholas Yasillo; Bruce D. Perry; Deborah Levy; Chin-Tu Chen; Claude Ortega; Robert N. Beck; Malcolm Cooper

Book ID
115883464
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
148 KB
Volume
175
Category
Article
ISSN
0014-2999

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Quantitation of striatal and extrastriat
Quantitation of striatal and extrastriatal D-2 dopamine receptors using PET imaging of [18F]fallypride in nonhuman primates
✍ Bradley T. Christian; Tanjore K. Narayanan; Bingzhi Shi; Jogeshwar Mukherjee πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 143 KB πŸ‘ 1 views

[(18)F]Fallypride is a highly selective, high-affinity dopamine D-2 receptor ligand. The high affinity, K(D) = 30 pM, makes it a suitable candidate for visualizing both striatal and extrastriatal binding in the brain. In this work, dynamic PET studies of two macaque monkeys were acquired along with

Fluorinated benzamide neuroleptics. 1. R
Fluorinated benzamide neuroleptics. 1. Radiosynthesis of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(2[F-18]fluoroethyl)-2-methoxybenzamide: A potential fluorine-18 labeled PET radiotracer for dopamine D2 receptors
✍ Jogeshwar Mukherjee; Bruce D. Perry; Malcolm Cooper πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 French βš– 360 KB

## Abstract The synthesis of a tosylate precursor for the radiosynthesis of a potential PET radiotracer, (S)‐N‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐(2‐[^18^F]fluoroethyl)‐2‐ methoxybenzamide is reported. Reaction of ^18^F‐fluoride with the tosylate provides the radiolabeled product in 10–25% yield. S