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PET Imaging of Dopamine D2 Receptors with [18F]Fluoroclebopride in Monkeys: Effects of Isoflurane- and Ketamine-Induced Anesthesia

✍ Scribed by Michael A Nader; Kathleen A Grant; H.Donald Gage; Richard L Ehrenkaufer; Jay R Kaplan; Robert H Mach


Book ID
114282299
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
185 KB
Volume
21
Category
Article
ISSN
1470-634X

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✍ Bradley T. Christian; Tanjore K. Narayanan; Bingzhi Shi; Jogeshwar Mukherjee πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 143 KB πŸ‘ 1 views

[(18)F]Fallypride is a highly selective, high-affinity dopamine D-2 receptor ligand. The high affinity, K(D) = 30 pM, makes it a suitable candidate for visualizing both striatal and extrastriatal binding in the brain. In this work, dynamic PET studies of two macaque monkeys were acquired along with