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Dominant lethal test with trichlorphon in male mice

✍ Scribed by K. Becker; J. Schöneich


Book ID
113249831
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
102 KB
Volume
74
Category
Article
ISSN
0165-1161

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Dominant lethal mutations in male mice
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Dominant lethal mutations are due to chromosome aberrations as demonstrated by analysis of first cleavage. With a sample size of 40-45 mice per dose the induction of dominant lethal mutations by 10 mg/kg of methyl methanesulfonat (MMS) can be detected in spermatids in the mating interval 9-12 days p