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Does galanin inhibit insulin secretion by opening of the ATP-regulated K+ channel in the β-cell?

✍ Scribed by Ahrén, Bo; Berggren, Per-Olof; Bokvist, Krister; Rorsman, Patrik


Book ID
123188864
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
446 KB
Volume
10
Category
Article
ISSN
0196-9781

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Anoxia opens ATP regulated K channels in
✍ K. Benndorf; M. Friedrich; Hj. Hirche 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 333 KB

We studied single channel ionic currents in cell-attached patches of guinea pig heart cells under conditions of anoxia (pO2 less than 0.1 torr) to identify the type of channels which contribute to the anoxia-induced time-independent K current in whole cells. In most experiments, K currents were reco