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Inhibition of ATP-regulated K+-channels by a photoactivatable ATP-analogue in mouse pancreatic β-cells

✍ Scribed by Carina Ämmälä; Krister Bokvist; Sheila Galt; Patrik Rorsman

Book ID
119510498
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
290 KB
Volume
1092
Category
Article
ISSN
0167-4889

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Glucose dependent K+-channels in pancrea
Glucose dependent K+-channels in pancreaticβ-cells are regulated by intracellular ATP
✍ P. Rorsman; G. Trube 📂 Article 📅 1985 🏛 Springer 🌐 English ⚖ 617 KB

The resting conductance of cultured ]?-cells from murine pancreases was investigated using the whole-cell, cell-attached and isolated patch modes of the patch-clamp technique. Whole-cell experiments revealed a high input resistance of the cells (>20 GO per cell or > 100 kg? -cm2), if the medium dial