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Does domain swapping improve the stability of RNase A?

โœ Scribed by F. Grant Pearce; Michael D.W. Griffin; Juliet A. Gerrard

Book ID
116298315
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
461 KB
Volume
382
Category
Article
ISSN
0006-291X

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โœ Katherine H. Miller; Susan Marqusee ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Cold Spring Harbor Laboratory Press ๐ŸŒ English โš– 347 KB

## Abstract Domain swapping is a type of oligomerization in which monomeric proteins exchange a structural element, resulting in oligomers whose subunits recapitulate the native, monomeric fold. It has been implicated as a potential mechanism for protein aggregation, which provides a strong impetus