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Doehlert experimental design applied to optimization and quality control of a granulation process in a high shear mixer

โœ Scribed by D. Vojnovic; D. Chicco; H. El Zenary


Book ID
114248504
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
522 KB
Volume
145
Category
Article
ISSN
0378-5173

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๐Ÿ“œ SIMILAR VOLUMES


Melt granulation in a high shear mixer:
โœ B Campisi; D Vojnovic; D Chicco; R Phan-Tan-Luu ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 781 KB

Melt granulation of a formulation of theophylline, containing lactose, microcrystalline cellulose and hydroxypropylmethylcellulose as excipients, was investigated in a 10 l high shear mixer as an alternative method to the wet granulation process, using polyethylene glycol 6000 as melting binder. The