✦ LIBER ✦

DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193

✍ Scribed by N. Hajji; N. Pastor; S. Mateos; I. Domı&#x0301;nguez; F. Cortés

Book ID: 114070821
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 318 KB
Volume: 530
Category: Article
ISSN: 0027-5107
DOI: 10.1016/s0027-5107(03)00135-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The SUMO pathway is required for selecti

The SUMO pathway is required for selective degradation of DNA topoisomerase IIβ induced by a catalytic inhibitor ICRF-193

✍ Sevim Isik; Kuniaki Sano; Kimiko Tsutsui; Masayuki Seki; Takemi Enomoto; Hisato 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 279 KB

Postincubation with aclarubicin reverses

Postincubation with aclarubicin reverses topoisomerase II mediated DNA cleavage, strand breaks, and cytotoxicity induced by VP-16

✍ Lone Nørgård Petersen; Peter Buhl Jensen; Boe Sandahl Sørensen; Svend Aage Engel 📂 Article 📅 1994 🏛 Springer US 🌐 English ⚖ 926 KB

Assessment of DNA double-strand breaks a

Assessment of DNA double-strand breaks and γH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone

✍ Daniel J. Smart; H. Dorota Halicka; Gabriele Schmuck; Frank Traganos; Zbigniew D 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 299 KB

Detection of topoisomerase inhibitor-ind

Detection of topoisomerase inhibitor-induced DNA strand breaks and apoptosis by the alkaline comet assay

✍ Thierry Godard; Edwige Deslandes; François Sichel; Jean-Michel Poul; Pascal Gaud 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 766 KB

Inhibition of topoisomerase II by ICRF-1

Inhibition of topoisomerase II by ICRF-193, the meso isomer of 2,3-bis(2,6-dioxopiperazin-4-yl)butane: Critical dependence on 2,3-butanediyl linker absolute configuration

✍ Robert M. Snapka; Sung Ho Woo; Andrei V. Blokhin; Donald T. Witiak 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 954 KB

DNA STRAND-BREAKS INDUCED BY THE TOPOISO

DNA STRAND-BREAKS INDUCED BY THE TOPOISOMERASE I INHIBITOR CAMPTOTHECIN IN UNSTIMULATED HUMAN WHITE BLOOD CELLS

✍ P. Daza; J. Torreblanca; G. Garcı́a-Herdugo; F.J. Moreno 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 358 KB

## Abstract Camptothecin (CPT) and actinomicyn‐induced strand‐breaks, repair and apoptosis in unstimulated human blood cells were studied using the DNA comet assay, and electrophoresis of low molecular weight DNA extracts. On the one hand, incubation of G0 leukocytes for 1h with CPT induced DNA str