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DNA repair: Time to switch

✍ Scribed by Wrighton, Katharine H.


Book ID
109959186
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
198 KB
Volume
10
Category
Article
ISSN
1471-0072

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## Abstract Poly(ADP‐ribosyl)ation is a post‐translational modification occurring in the nucleus. The most abundant and best‐characterized enzyme catalyzing this reaction, poly(ADP‐ribose) polymerase 1 (PARP1), participates in fundamental nuclear events. The enzyme functions as molecular β€œnick sens