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DNA repair gene XRCC1 polymorphisms, smoking, and esophageal cancer risk

✍ Scribed by Hong-Ping Yu; Xiao-Yong Zhang; Xiao-Li Wang; Lu-Yuan Shi; Yuan-Yuan Li; Fang Li; Yan-Hua Su; You-Jie Wang; Bin Lu; Xi Sun; Wen-Hong Lu; Shun-Qing Xu


Book ID
113524217
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
76 KB
Volume
28
Category
Article
ISSN
0361-090X

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Genetic polymorphisms of XRCC1 and risk
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A variety of environmental factors were identified to be associated with the risk of esophageal cancer. The variation in capacity of DNA repair might influence environmental chemical-associated carcinogenesis. We hypothesized that the polymorphic XRCC1 genes might modify cancer susceptibility of the