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DNA polymorphism and molecular pathology of the human globin gene clusters

โœ Scribed by Stylianos E. Antonarakis; Haig H. Kazazian; Stuart H. Orkin


Publisher
Springer
Year
1985
Tongue
English
Weight
508 KB
Volume
70
Category
Article
ISSN
0340-6717

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โœฆ Synopsis


Although the reference list of the above paper was alphabetized and renumbered accordingly during the editorial process, the numbers in the text were not changed to agree. Therefore, pp. 3 and 12-14 are being reprinted to agree with the text. Please substitute these pages for those originally published.


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Of the 645 Japanese subjects studied, we have identified 10 individuals heterozygous for a chromosome with the triplicated alpha-globin loci. The frequency of the triple alpha-loci was 0.008 in this population, while that of the single alpha-locus, i.e., alpha-thalassemia 2 gene, might be lower than