𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Detection of a restriction site polymorphism within the human α-globin gene complex

✍ Scribed by G. Assum; E. -U. Griese; J. Horst


Publisher
Springer
Year
1985
Tongue
English
Weight
256 KB
Volume
69
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Genetic polymorphisms of gene conversion
✍ Hitoshi Nakashima; Asao Fujiyama; Shunjiro Kagiyama; Takashi Imamura 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 438 KB

Of the 645 Japanese subjects studied, we have identified 10 individuals heterozygous for a chromosome with the triplicated alpha-globin loci. The frequency of the triple alpha-loci was 0.008 in this population, while that of the single alpha-locus, i.e., alpha-thalassemia 2 gene, might be lower than

Polymorphism of the Hinf I restriction s
✍ Gila Kohen; Noël Philippe; Jacqueline Godet 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 337 KB

Mapping of the DNA from 14 Mediterranean subjects indicates a genetic variation in an Hinf I recognition site located 1 kilobase 5' to the beta-globin gene. This Hinf I site was found associated with eight beta-thalassemic genes and 11 normal beta genes, and hence is not specifically linked to beta-

Hemoglobin K�ln: Analysis of linkage rel
✍ Horst, J. ;Oehme, R. ;Kleihauer, E. ;Kohne, E. 📂 Article 📅 1984 🏛 Springer-Verlag ⚖ 554 KB

Nuclear DNA has been analyzed by means of restriction endonuclease mapping procedure to identify chromosomes that carry mutant Hb Köln beta-globin genes in a family with individuals heterozygous for this disease. Inherited DNA polymorphisms within the beta-globin gene cluster yielded a direct linkag