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Polymorphism of the Hinf I restriction site located 1 Kb 5′ to the human β-globin gene

✍ Scribed by Gila Kohen; Noël Philippe; Jacqueline Godet

Publisher: Springer
Year: 1982
Tongue: English
Weight: 337 KB
Volume: 62
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00282298

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✦ Synopsis

Mapping of the DNA from 14 Mediterranean subjects indicates a genetic variation in an Hinf I recognition site located 1 kilobase 5' to the beta-globin gene. This Hinf I site was found associated with eight beta-thalassemic genes and 11 normal beta genes, and hence is not specifically linked to beta-thalassemia.

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