✦ LIBER ✦

DNA methyltransferase polypeptides in mouse and human cells

✍ Scribed by Gerd P. Pfeifer; Dusan Drahovsky

Book ID: 119119482
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 525 KB
Volume: 868
Category: Article
ISSN: 0167-4781
DOI: 10.1016/0167-4781(86)90059-x

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## Abstract Recent studies have shown that cytosine‐5 methylation at CpG islands in the regulatory sequence of a gene is one of the key mechanisms of inactivation. The enzymes responsible for CpG methylation are DNA methyltransferase (DNMT) 1, DNMT3a, and DNMT3b, and the enzyme responsible for deme