DNA methylation: TET proteins—guardians of CpG islands?
✍ Scribed by Williams, Kristine (author);Christensen, Jesper (author);Helin, Kristian (author)
- Book ID
- 121873750
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 307 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1469-221X
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Articles In The Fields Of Biochemistry And Physiology, Cell Biology, Developmental Biology, Ecology, Evolution, Genetics, Immunology, Molecular Biology, Neuroscience, Microbiology And Virology, Plant Science, Structural Biology, Science And Society. Includes Index.
DNA methylation is the epigenetic modification, which introduces 5mC as fifth base onto DNA. As for the distribution of 5mCs, it is well known that they distribute themselves in a non-random fashion in genomic DNA so that methylation pattern is characterized by the presence of methylated cytosines o