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Distribution of DNA methylation, CpGs, and CpG islands in human isochores

✍ Scribed by Annalisa Varriale; Giorgio Bernardi

Book ID
116981902
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
304 KB
Volume
95
Category
Article
ISSN
0888-7543

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DNA methylation is the epigenetic modification, which introduces 5mC as fifth base onto DNA. As for the distribution of 5mCs, it is well known that they distribute themselves in a non-random fashion in genomic DNA so that methylation pattern is characterized by the presence of methylated cytosines o