Transcriptional inactivation of the tiss
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Shin Hyeok Kang; Hyun Ho Choi; Sang Gyun Kim; Hyun-Soon Jong; Noe Kyeong Kim; Se
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Article
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2000
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John Wiley and Sons
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French
β 87 KB
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The tissue inhibitor of metalloproteinase-3 (TIMP-3), a recently cloned member of TIMP gene family, has been implicated in the negative regulation of tumor cell invasion and tumor growth. Down-regulation of this gene has been shown to occur in a mouse carcinogenesis model, suggesting that it might p