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CpG-rich islands and the function of DNA methylation

✍ Scribed by Bird, Adrian P.

Book ID
109743664
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
508 KB
Volume
321
Category
Article
ISSN
0028-0836

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DNA methylation is the epigenetic modification, which introduces 5mC as fifth base onto DNA. As for the distribution of 5mCs, it is well known that they distribute themselves in a non-random fashion in genomic DNA so that methylation pattern is characterized by the presence of methylated cytosines o